The Formation of Collagen Fibers by the Action of Heparin on Soluble Collagen: an Electron Microscope Study
نویسنده
چکیده
Collagen fibers have been formed in vitro by the action of heparm on solutions of collagen. Heparin was found to be effective in inducing collagen fiber formation when present in concentrations as low as 1-80,000. It is postulated that mast cells, by virtue of the heparin which they produce, may play a role in the formation of collagen.
منابع مشابه
Comparative Study of Clinical Staging of Oral Submucous Fibrosis with Qualitative Analysis of Collagen Fibres Under Polarized Microscopy
Background & Objectives: Oral submucous fibrosis (OSMF) is a condition where excessive deposition of dense collagen fibers occurred in the connective tissue of oral mucosa. An alteration of collagen necessitates an in depth understanding of collagen in oral tissues as no breakthrough studies have been reported. Therefore the aim was to correlate the clinical, functional and histopathol...
متن کاملEffect of Collagen Gel on Sciatic Nerve Regeneration in the Polyvinylidene Fluoride Tube
Background: The limited availability of donor sites for nerve grafting has continued to stimulate research toward finding suitable alternatives for autograft. The aim of this research was to study the effect of piezoelectric channel and collagen gel on nerve regeneration. Materials and methods: This research is an experimental study. Forty eight male rats (200-250 gr) were used. After axotomy...
متن کاملIsolation and characterization of acid-soluble collagen from the skin of Rutilus Frisii Kutum (Kamensky) of the Caspian Sea
This study proceeds to extract collagen from the skin of Rutilus kutum, one of the main and economical species of the Caspian Sea. Acid-soluble collagen (ASC) from the skin of R. kutum was extracted and characterized by SDS-PAGE, FTIR and UV spectrophotometry. Based on the data from the SDS-PAGE and the composition of amino acid, it was probable that the obtained collagen classified as type I...
متن کاملHistochemical and Immunohistochemical Analysis of Collagen Fibers and Microvascular Density in Various Grades of Oral Submucous Fibrosis
Background and Objective: This study was aimed to evaluate the collagen fibers qualitatively and its correlation with microvascular density in various grades of oral submucous fibrosis (OSMF). Material and Methods: The present study comprised of total 40 cases of oral submucous fibrosis. Picrosirius red staining was done on all the specimens’ sections. ...
متن کاملObservations with the Electron Microscope on the Solvation and Reconstitution of Collagen
The course of events in the solvation and reconstitution of collagen obtained from rat tail tendon is described as seen with the electron microscope. Under the influence of 0.01 per cent acetic acid the collagen fibers swell and dissociate into submicroscopic filaments, the smallest of which are probably beyond the resolution of the electron microscope. These filaments can be made to reconstitu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- The Journal of Experimental Medicine
دوره 96 شماره
صفحات -
تاریخ انتشار 1952